Five kilograms of liquid carbon tetrachloride undergo a mechanically reversible. Tenant notification fact sheet for carbon tetrachloride is available in portable document format pdf, 24kb this fact sheet is provided to fulfill new york state department of health requirements for preparation of generic fact sheets under article 27 title 24, section 272405 of the environmental conservation law. The world health organization has established an international drinkingwater guideline for carbon tetrachloride of 2. Carbon tetrachloride has a low potential to bioconcentrate. Please make sure this information is given to them. It compiles information from several government agencies and organizations. Eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Carbon tetrachloride and mixtures containing it with the exception of chemicals containing unavoidable residues of carbon tetrachloride that do not result in atmospheric concentrations of carbon tetrachloride greater than 10 ppm are banned from consumer products. Chemical identification and physical properties exposure limits sampling information. Files are available under licenses specified on their description page. The brita products company 1221 broadway oakland, ca 94612 tel. Carbon tetrachloride ccl 4, a volatile inorganic compound, is a very welldescribed hepatotoxicant.
Until 1986, the chemical was used as a grain fumigant. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Carbon tetrachloride 10 lb 1 lb california proposition 65 this product contains the following proposition 65 chemicals. Values of 1065 mgm3 have been used as standards or guidelines in other countries international labour office, 1991. Titanium tetrachloride, 99% safety data sheet inti065. This fact sheet is provided to fulfill new york state department of health requirements for preparation of generic fact sheets under article 27 title 24, section 272405 of the environmental conservation law. Uses advised against food, drug, pesticide or biocidal product use. Sep 26, 2019 toxicological profile for carbon tetrachloride. This monograph is one in a series of selfinstructional.
Carbon tetrachloride is an important commercial chemical. First aid eye contact immediately flush with large amounts of cool water for at. All atsdr toxicological profile pdf files are electronic conversions from paper copy or other electronic ascii text files. Carbon tetrachloride is most often found in the air as a colorless gas. However, when heated to decomposition, it will emit fumes of extremely toxic phosgene and of hydrogen chloride. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Concentrated nitric and sulfuric acid mixtures, oxidizing materials, chloroform, alkalis, chlorine compounds, acids, potassium tbutoxide. Workers had elevated levels of acetone in samples of expired alveolar gas and thus were metabolically predisposed to carbon tetrachloride. Carbon tetrachloride is a manmade clear liquid with a strong, sweet odor that smells like chloroform.
Carbon tetrachloride, also known by many other names such as tetrachloromethane, also recognised by the iupac, carbon tet in the cleaning industry, halon104 in firefighting, and refrigerant10 in hvacr is an organic compound with the chemical formula ccl 4. White plastic cylindrical cartridge containing ion exchange resin and activated carbon other designations distributor emergency telephone nos. Draft risk evaluation for carbon tetrachloride pdf 301 pp, 4 mb draft charge to the panel for carbon tetrachloride pdf. Use water spray, alcoholresistant foam, dry chemical or carbon dioxide. Carbon tetrachloride boils at 77 c 171 f and freezes at 23 c 9 f. Chemical product and company identification boc gases, division of the boc group, inc. Ccl 4 was once widely used as a dry cleaning solvent, precursor to refrigerant synthesis, propellant for aerosol cans, a fire extinguishing liquid, as a solvent for oils, fats, and lacquers, as a grain fumigant and curiously enough, in lava lamps 30, 31.
Occupational risk calculations 206 k you may need a pdf reader to view some of the files on this page. It is a colourless liquid with a sweet smell that can be detected at low levels. Chemical product and company identification product name. Carbon tetrachloride, carbon tetrachloride hazard class. Carbon tetra chloride material safety data sheet cas.
Weve included the most sought after safety data sheets. If the spilled material is flammable, extinguish all open flames. The international programme on chemical safetys report on carbon tetrachloride. Liver irregularities based on human evidence carbon tetrabromide section 12.
Tenant notification fact sheet for carbon tetrachloride. Carbon tetrachloride wisconsin department of health services. Carbon tetrachloride an overview sciencedirect topics. This chemical is on the special health hazard substance list. If inhaled if breathed in, move person into fresh air. Acetone, a product of isopropyl alcohol metabolism, is a major potentiator of carbon tetrachloride toxicity. It may be found in both ambient outdoor and indoor air. Epa is announcing the availability of and soliciting public comment on the draft toxic substances control act tsca risk evaluation of carbon tetrachloride. Linking to a nonfederal website does not constitute an endorsement by cdc or any of its employees of the sponsors or the information and products presented on the website.
Sigmaaldrich 319961 page3 of 9 in case of eye contact rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Ccl 4 has become a model for the study of agents that cause localized cellular injury via a freeradical mechanism. When administered by gavage, carbon tetrachloride increased the incidence of hepatomas and hepatocellular carcinoma in mice of both sexes. Carbon tetrachloride has a mutagenic effect and induces aneuploidy in several invitro systems. An explosion can occur if either a carbon tetrachloride or a dry ammonium compound fire extinguisher is used to extinguish a fire involving calcium hypochlorite. Once absorbed it is widely found in fat but also in blood, muscle, liver, brain and other tissues and organs. It is also called carbon chloride, methane tetrachloride, perchloromethane, tetrachloroethane, or benziform. In a fire or if heated, a pressure increase will occur and the container may burst or explode. Carbon tet is still used to manufacture propellants and other industrial chemicals. The primary effects of carbon tetrachloride in humans are on the liver, kidneys, and central nervous system. Carbon tetrachloride is on the right to know hazardous substance list because it is cited by osha, acgih, dot, niosh, ntp, dep, iarc, nfpa and epa.
Niosh considers carbon tetrachloride to be a potential occupational carcinogen as defined by the osha carcinogen policy 29 cfr 1990. Treatment consists of support of treatment consists of support of respiratory, cardiovascular, hepatic, and renal functions. Our msds database is an easy to use, do it yourself tool, and best of all. Carbon tetrachloride is also a common contaminant of indoor air. Carbon bisulfide safety data sheet ghs product identifier other means of identification 24hour telephone section 1. Carbon tetra chloride material safety data sheet cas no 56. Carbon tetrachloride is a chlorinated organic solvent. On completion of the carbon tetrachloride toxicity csem you will be able to. Carbon tetrachloride product stewardship summary version 2017. Product has an indefinite shelf life if stored in original container in a cool, dry place. Carbon tetrachloride is a commonly used liquid in fire extinguishers to combat small fires.
The most recent work in this field has inaugurated a third revolution in the study of carbon tetrachloride hepatotoxicity. Carbon tetrachloride can be manufactured by the chlorination of methyl chloride according to the following reaction. The hazard of systemic effects is increased when carbon tetrachloride is used in conjunction with ingested alcohol. Carbon tetrachloride induces hepatic cell proliferation and dna synthesis. Identification product name carbon tetrachloride cat no. It is a known animal carcinogen and a potential human carcinogen. In case of skin contact wash off with soap and plenty of water. There is no antidote for carbon tetrachloride poisoning. Firefighters should wear appropriate protective equipment and selfcontained breathing.
This page was last edited on 15 november 2017, at 23. Carbon tetrachloride ccl4 chemical abstracts service cas number. Carbon tetrachloride carbon tet is a nonflammable colorless liquid with a heavy, sweet odor. Safety data sheet creation date 24nov2010 revision date 18jan2018 revision number 3 1. In particular, for carbon tetrachloride poisoning, at a time when liver triglycerides are increasing rapidly, there is no increase in flux of fatty acids through the plasma compartment. Links with this icon indicate that you are leaving the cdc website the centers for disease control and prevention cdc cannot attest to the accuracy of a nonfederal website. Safety data sheet rochester institute of technology. Preliminary information on manufacturing, processing. Carbon tetrachloride is a manmade volatile organic chemical that was used as a household.
Sds of carbon tetrachloride, safety data sheets, cas 56235. Scorecards chemical profile on carbon tetrachloride. The us epas drinking water regulations and contaminants. This conversion may have resulted in character translation or format errors. Carbon tetrachloride production and use peaked in the 1970s and was driven further downward after the montreal protocol on substances that deplete the ozone layer was agreed to in 1987. Identification of the substancemixture and of the companyundertaking 1. When administered by inhalation carbon tetrachloride induced liver carcinomas in rats.
These features were considered to be evidence in favour of a direct hepatotoxic effect of carbon tetrachloride, and are difficult to reconcile with the view, formulated again recently by some workers, that carbon tetrachloride acts indirectly on the liver cell by producing vasoconstriction. Wear normal fire kit in combination with breathing apparatus. Integrated risk information system iris march 2010. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Carbon tetrachloride is a manufactured chemical that does not occur naturally. Releases of carbon tetrachloride in quantities equal to or greater than the reportable quantity rq of 10 pounds are subject to reporting to the national response center under cercla, section 304 sara title. Carbon tetrachloride is preferred in this process as it is the only solvent not attacked by chlorine. It is a clear liquid with a sweet smell that can be detected at low levels. All structured data from the file and property namespaces is available under the creative commons cc0 license. Show this safety data sheet to the doctor in attendance. As a volatile organic compound voc, carbon tetrachloride easily vaporizes. Carbon tetrachloride was widely used as a dry cleaning solvent, as a refrigerant, and in lava lamps. Carbon tetrachloride is a clear, nonflammable liquid which is almost insoluble in water. In case of the latter, carbon tetrachloride is a key ingredient that adds weight to the otherwise buoyant wax.
Draft risk evaluation for carbon tetrachloride assessing. It once was a popular solvent in organic chemistry, but, because of its adverse health effects, it is rarely used today. Chemical spills the following actions must be taken in the event of a chemical spill. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Carbon tetrachloride was once very widely used as a dry cleaning agent, fire extinguisher and grain fumigant. Titanium tetrachloride, 99% safety data sheet 08312015 en english us sds id. Bioconcentration factor predicted from water solubility 14.
Before 1970, carbon tet was widely used as a cleaning fluid in home and industry. Oxychem manufactures carbon tetrachloride at facilities in geismar, louisiana and wichita. Carbon tetrabromide material safety data sheet cas. In a prospective cohort study seidler 1999, the association between maternal occupational exposure to specific chemical substances among these carbon tetrachloride and the birth of smallforgestationalage sga infants was evaluated. Formerly used as a drycleaning solvent, carbon tetrachloride has been almost entirely displaced from this application by tetrachloroethylene, which is much more stable and less toxic. Osha occupational chemical database occupational safety and. General advice show this safety data sheet to the doctor in attendance. Ld50 20 carbon tetrachloride is harmful to the liver and a cns depressant following shortterm inhalation, skin contact or ingestion. This iris assessment for carbon tetrachloride consists of hazard identification and doseresponse assessment data and provides support for epa risk management decisions. Carbon tetrachloride is readily absorbed by all routes of exposure inhalation, oral and dermal in both humans and experimental animals. Ac148170025 synonyms tetrachloromethane recommended use laboratory chemicals. The liver effects have been observed at concentrations lower than those required to produce cns effects. It is used as a solvent and to make other chemicals.
Avoid breathing vapors or dust when opening container. Carbon dioxide and carbon monoxide may form when heated to decomposition. It also contains information to help you meet community right to know emergency response reporting requirements under sara title iii and many other laws. Where can carbon tetrachloride be found and how is it used. Acetone revision date 25apr2019 skin contact wash off immediately with plenty of water for at least 15 minutes. Transport information dot unno 1846 proper shipping name carbon tetrachloride hazard class 6. Carbon tetrachloride ccl 4 is regarded as highly toxic. At concentrations above the niosh rel, or where there is no rel, at any detectable concentration. The resulting resins are thermoplastic, odorless, and non toxic. Carbon tetrachloride is used for producing other chemicals. Toxic effect of carbon tetrachloride on the liver cell. Apf 10,000 any selfcontained breathing apparatus that has a full facepiece and is operated in a pressuredemand or other positivepressure mode. Safety data sheet northwest missouri state university. Carbon tetrachloride ccl4 chemical abstracts service.
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